发明申请
US20100298361A1 Alkylthio Pyrimidines As CRTH2 Antagonists 有权
烷硫基嘧啶类作为CRTH2拮抗剂

  • 专利标题: Alkylthio Pyrimidines As CRTH2 Antagonists
  • 专利标题(中): 烷硫基嘧啶类作为CRTH2拮抗剂
  • 申请号: US12679895
    申请日: 2008-09-24
  • 公开(公告)号: US20100298361A1
    公开(公告)日: 2010-11-25
  • 发明人: Tai Wei Ly
  • 申请人: Tai Wei Ly
  • 优先权: US60995386 20070925
  • 国际申请: PCT/US08/11053 WO 20080924
  • 主分类号: A61K31/505
  • IPC分类号: A61K31/505 C07D239/58 A61P11/06 A61P35/04 A61P17/06 A61P19/02
Alkylthio Pyrimidines As CRTH2 Antagonists
摘要:
Provided herein are alkylthio substituted pyrimidine compounds having CRTH2 (G-protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity, useful for the treatment or prophylaxis of diseases associated with CRTH2 activity, including the treatment of allergic diseases, eosinophil-related diseases and basophil-related diseases.
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