发明申请
- 专利标题: Alkylthio Pyrimidines As CRTH2 Antagonists
- 专利标题(中): 烷硫基嘧啶类作为CRTH2拮抗剂
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申请号: US12679895申请日: 2008-09-24
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公开(公告)号: US20100298361A1公开(公告)日: 2010-11-25
- 发明人: Tai Wei Ly
- 申请人: Tai Wei Ly
- 优先权: US60995386 20070925
- 国际申请: PCT/US08/11053 WO 20080924
- 主分类号: A61K31/505
- IPC分类号: A61K31/505 ; C07D239/58 ; A61P11/06 ; A61P35/04 ; A61P17/06 ; A61P19/02
摘要:
Provided herein are alkylthio substituted pyrimidine compounds having CRTH2 (G-protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity, useful for the treatment or prophylaxis of diseases associated with CRTH2 activity, including the treatment of allergic diseases, eosinophil-related diseases and basophil-related diseases.
公开/授权文献
- US08324229B2 Alkylthio pyrimidines as CRTH2 antagonists 公开/授权日:2012-12-04
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