发明申请
US20100298362A1 PROCESS FOR THE PREPARATION OF 4-[6-(6-METHANESULFONYL-2-METHYL-PYRIDIN-3-YLAMINO)-5-METHOXY-PYRIMIDIN-4-YLOXY]-PIPERIDINE-1-CARBOXYLIC ACID ISOPROPYL ESTER
审中-公开
制备4- [6-（6-甲磺酰基-2-甲基 - 吡啶-3-基）氨基] -5-甲氧基 - 嘧啶-4-基] - 哌啶-1-羧酸异丙酯的方法
![PROCESS FOR THE PREPARATION OF 4-[6-(6-METHANESULFONYL-2-METHYL-PYRIDIN-3-YLAMINO)-5-METHOXY-PYRIMIDIN-4-YLOXY]-PIPERIDINE-1-CARBOXYLIC ACID ISOPROPYL ESTER](/docs/US/2010-11-25/US20100298362A1/abs.jpg.600x600.jpg)
- 专利标题： PROCESS FOR THE PREPARATION OF 4-[6-(6-METHANESULFONYL-2-METHYL-PYRIDIN-3-YLAMINO)-5-METHOXY-PYRIMIDIN-4-YLOXY]-PIPERIDINE-1-CARBOXYLIC ACID ISOPROPYL ESTER
- 专利标题（中）： 制备4- [6-（6-甲磺酰基-2-甲基 - 吡啶-3-基）氨基] -5-甲氧基 - 嘧啶-4-基] - 哌啶-1-羧酸异丙酯的方法
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申请号： US12783927申请日： 2010-05-20
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公开(公告)号： US20100298362A1公开(公告)日： 2010-11-25
- 发明人: Xun Li , Ken Wells , Shawn Branum , Sandra Damon
- 申请人： Xun Li , Ken Wells , Shawn Branum , Sandra Damon
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D239/553 ; A61P3/00
![PROCESS FOR THE PREPARATION OF 4-[6-(6-METHANESULFONYL-2-METHYL-PYRIDIN-3-YLAMINO)-5-METHOXY-PYRIMIDIN-4-YLOXY]-PIPERIDINE-1-CARBOXYLIC ACID ISOPROPYL ESTER](/abs-image/US/2010/11/25/US20100298362A1/abs.jpg.150x150.jpg)
摘要：
The present invention is directed to a process for the preparation of 4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methoxy-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester, useful as glucose dependent insulinotropic receptor agonist, for the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity.