发明申请
US20100298380A1 N-ARYL-N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THIER USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS
审中-公开
N-ARYL-N-哌啶-4-甲酰胺衍生物,并用作单胺神经递质抑制剂
- 专利标题: N-ARYL-N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THIER USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS
- 专利标题(中): N-ARYL-N-哌啶-4-甲酰胺衍生物,并用作单胺神经递质抑制剂
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申请号: US12671592申请日: 2008-07-31
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公开(公告)号: US20100298380A1公开(公告)日: 2010-11-25
- 发明人: Dan Peters , John Paul Redrobe , Gordon Munro , Elsebet Østergaard Nielsen
- 申请人: Dan Peters , John Paul Redrobe , Gordon Munro , Elsebet Østergaard Nielsen
- 申请人地址: DK Ballerup
- 专利权人: NeuroSearch A/S
- 当前专利权人: NeuroSearch A/S
- 当前专利权人地址: DK Ballerup
- 优先权: DKPA200701114 20070802
- 国际申请: PCT/EP08/60034 WO 20080731
- 主分类号: A61K31/454
- IPC分类号: A61K31/454 ; C07D401/06 ; A61P29/00 ; A61P25/28 ; A61P25/22 ; A61P25/00 ; A61P25/24 ; A61P25/30 ; A61P19/02 ; A61P1/00 ; A61P15/00 ; A61P43/00 ; A61P25/32 ; A61P25/34
摘要:
This invention relates to novel N-aryl-N-piperidin-4-ylmethyl amide derivatives useful as monoamine neurotransmitter re-uptake inhibitors.In other aspects the invention relates to the use of these compounds in a method for therapy, and to pharmaceutical compositions comprising the compounds of the invention.