发明申请
- 专利标题： MODULATION OF FACTOR 7 EXPRESSION
- 专利标题（中）： 因子7的表达式的调制
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申请号： US12741959申请日： 2008-11-05
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公开(公告)号： US20100298417A1公开(公告)日： 2010-11-25
- 发明人: Susan M. Freier , Brett P. Monia , Hong Zhang , Jeffrey R. Crosby , Chenguang Zhao
- 申请人： Susan M. Freier , Brett P. Monia , Hong Zhang , Jeffrey R. Crosby , Chenguang Zhao
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 国际申请： PCT/US08/82526 WO 20081105
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; C07H21/04
摘要：
Disclosed herein are antisense compounds and methods for decreasing Factor 7 and treating or preventing thromboembolic complications, hyperproliferative disorders, or inflammatory conditions in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 7 include thrombosis, embolism, and thromboembolism, such as, deep vein thrombosis, pulmonary embolism, myocardial infarction, stroke, cancer, rheumatoid arthritis, and fibrosis.
公开/授权文献
- US09029337B2 Modulation of factor 7 expression 公开/授权日：2015-05-12
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