发明申请
- 专利标题： SELECTIVE AGONIST OF TOLL-LIKE RECEPTOR 3
- 专利标题（中）： 选择性激素受体3受体3
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申请号： US12735755申请日： 2009-02-17
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公开(公告)号： US20100310600A1公开(公告)日： 2010-12-09
- 发明人: William A. Carter , David Strayer
- 申请人： William A. Carter , David Strayer
- 国际申请： PCT/US2009/000959 WO 20090217
- 主分类号： A61K31/7105
- IPC分类号： A61K31/7105 ; A61K39/12 ; A61K39/02 ; A61K39/00 ; A61K39/002 ; A61P35/04 ; A61P33/00 ; A61P31/04 ; A61P31/12
摘要：
A mismatched double-stranded ribonucleic acid, which is an agonist for Toll-like receptor 3 (TLR3), is used in vitro or in vivo as an antimicrobial agent, antiproliferative agent, and/or immunostimulant. Poly(l:C11-14U) is a more selective agonist of TLR3 as compared to poly(l:C) even though the both double-stranded RNA are structurally analogous.
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