发明申请
US20100311798A1 2-AMINOOXAZOLINES AS TAAR1 LIGANDS 审中-公开
2-AMINOOXAZOLINES as TAAR1 LIGANDS

2-AMINOOXAZOLINES AS TAAR1 LIGANDS
摘要:
The invention relates to compounds of formula wherein R1, R2, R2′, X, Y, andn are as defined in the specification or to a pharmaceutically suitable acid addition salt thereof. The compounds of formula I are active on the TAAR1 receptor and are therefore suitable for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder, stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, substance abuse and metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
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