发明申请
- 专利标题: Metabotropic Glutamate-Receptor-Potentiating Isoindolones
- 专利标题(中): 代谢型谷氨酸受体 - 加强异吲哚酮
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申请号: US12861336申请日: 2010-08-23
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公开(公告)号: US20100317674A1公开(公告)日: 2010-12-16
- 发明人: Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James R. Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
- 申请人: Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James R. Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
- 主分类号: A61K31/497
- IPC分类号: A61K31/497 ; C07D209/44 ; C07D401/12 ; C07D401/02 ; C07D403/02 ; C07D403/14 ; C07D417/02 ; A61K31/4035 ; A61K31/4439 ; A61K31/427 ; A61P25/28 ; A61P25/00 ; A61P25/30 ; A61P25/18 ; A61P25/22 ; A61P25/24 ; A61P29/00 ; A61P25/16 ; A61P25/08 ; A61P25/06 ; A61P9/00 ; A61P9/10
摘要:
Compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined in the description, processes for the preparing the compounds, new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and uses of the compounds in therapy.
公开/授权文献
- US08153638B2 Metabotropic glutamate-receptor-potentiating isoindolones 公开/授权日:2012-04-10
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