发明申请
US20100317704A1 SPIRO-CONDENSED IMIDAZOLONE DERIVATIVES INHIBITING THE GLYCINE TRANSPORTER
审中-公开
螺旋状咪唑啉酮衍生物抑制糖蛋白转运蛋白
- 专利标题: SPIRO-CONDENSED IMIDAZOLONE DERIVATIVES INHIBITING THE GLYCINE TRANSPORTER
- 专利标题(中): 螺旋状咪唑啉酮衍生物抑制糖蛋白转运蛋白
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申请号: US12676625申请日: 2008-09-09
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公开(公告)号: US20100317704A1公开(公告)日: 2010-12-16
- 发明人: Richard Blunt , David Gwyn Cooper , Roderick Alan Porter , Paul Adrian Wyman
- 申请人: Richard Blunt , David Gwyn Cooper , Roderick Alan Porter , Paul Adrian Wyman
- 专利权人: Glaxo Group Limited a corporation
- 当前专利权人: Glaxo Group Limited a corporation
- 优先权: GB0717728.0 20070911; GB0802586.8 20080212; GB0813501.4 20080723
- 国际申请: PCT/EP2008/061889 WO 20080909
- 主分类号: A61K31/4188
- IPC分类号: A61K31/4188 ; C07D487/10 ; A61K31/4184 ; A61P25/28 ; A61P25/18
摘要:
Compounds of formula (I) and salts thereof are provided: wherein the groups are as defined in the specification. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.