发明申请
- 专利标题： Methods for purifying baculovirus
- 专利标题（中）： 杆状病毒纯化方法
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申请号： US12081065申请日： 2008-04-10
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公开(公告)号： US20100323429A1公开(公告)日： 2010-12-23
- 发明人: Yu-Chen Hu , Guan-Yu Chen
- 申请人： Yu-Chen Hu , Guan-Yu Chen
- 主分类号： C12N7/02
- IPC分类号： C12N7/02
摘要：
The present invention provides a method for purifying baculovirus comprising: providing a baculovirus mixture containing a baculovirus and a liquid portion; replacing the liquid portion with a binding buffer by an ultrafiltration system to form a virus buffer; and purifying the baculovirus from the virus buffer using glycoprotein specific affinity chromatography. Therefore, use of the method of the present invention in the purification of baculovirus resulted in an enhanced discovery yield and improved purity of virus.
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