发明申请
US20100324070A1 INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS
有权
吲哚，吲哚和苯并咪唑类亚胺基作为P2X3和P2X2 / 3拮抗剂
- 专利标题： INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS
- 专利标题（中）： 吲哚，吲哚和苯并咪唑类亚胺基作为P2X3和P2X2 / 3拮抗剂
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申请号： US12820748申请日： 2010-06-22
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公开(公告)号： US20100324070A1公开(公告)日： 2010-12-23
- 发明人: Michael Patrick Dillon , Nancy Elisabeth Krauss
- 申请人： Michael Patrick Dillon , Nancy Elisabeth Krauss
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; C07D401/14 ; A61P29/00 ; A61P17/02 ; A61P25/06 ; A61P31/04 ; A61P9/10 ; A61P1/00 ; A61P15/00
摘要：
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, X, Y, Z, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
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