发明申请
US20100330143A1 MODIFIED MACROMOLECULES AND METHODS OF MAKING AND USING THEREOF
审中-公开
改良的大分子及其制备和使用方法
- 专利标题： MODIFIED MACROMOLECULES AND METHODS OF MAKING AND USING THEREOF
- 专利标题（中）： 改良的大分子及其制备和使用方法
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申请号： US12764466申请日： 2010-04-21
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公开(公告)号： US20100330143A1公开(公告)日： 2010-12-30
- 发明人: Glenn D. Prestwich , Aleksander Skardal , Jianxing Zhang
- 申请人： Glenn D. Prestwich , Aleksander Skardal , Jianxing Zhang
- 申请人地址： US UT Salt Lake City
- 专利权人： UNIVERSITY OF UTAH RESEARCH FOUNDATION
- 当前专利权人： UNIVERSITY OF UTAH RESEARCH FOUNDATION
- 当前专利权人地址： US UT Salt Lake City
- 主分类号： C07K14/78
- IPC分类号： C07K14/78 ; C08B37/00 ; C08G63/91 ; C08F120/10 ; A61K31/728 ; A61K38/39 ; A61K31/74 ; A61F2/00 ; B05D5/00 ; C12Q1/02 ; C12N5/073
摘要：
Described herein are composites produced by reacting a first thiolated macromolecule with at least one compound having at least one thiol-reactive electrophilic functional group. The methods described herein permit the cross-linking of a variety of different thiolated macromolecules with one another. The composites described herein have a variety of biomedical and pharmaceutical applications, which are also described herein.