Invention Application
- Patent Title: 2-CARBOXAMIDE-7-PIPERAZINYL-BENZOFURAN DERIVATIVES 774
- Patent Title (中): 2-羧酰胺-7-哌嗪基苯并呋喃衍生物774
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Application No.: US12824567Application Date: 2010-06-28
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Publication No.: US20100331341A1Publication Date: 2010-12-30
- Inventor: Johan ANDERSSON , Helena GYBÄCK , Anh JOHANSSON , Christian Erik LINDE , Jonas MALMSTRÖM , Gunnar NORDVALL , Tatjana WEIGELT , Gitte TERP
- Applicant: Johan ANDERSSON , Helena GYBÄCK , Anh JOHANSSON , Christian Erik LINDE , Jonas MALMSTRÖM , Gunnar NORDVALL , Tatjana WEIGELT , Gitte TERP
- Applicant Address: SE Sodertalje
- Assignee: ASTRAZENECA AB
- Current Assignee: ASTRAZENECA AB
- Current Assignee Address: SE Sodertalje
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D405/14 ; A61P25/28 ; A61P25/24 ; A61P25/18 ; A61P25/00 ; A61P25/16

Abstract:
The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted; R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, optionally substituted; R3 is hydrogen or C1-4alkyl, or R2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substituted; R4 is hydrogen, halogen, methyl or methoxy; to pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders. The present invention further relates to new intermediates useful in the preparation thereof.
Public/Granted literature
- US08367676B2 2-carboxamide-7-piperazinyl-benzofuran derivatives 774 Public/Granted day:2013-02-05
Information query
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