发明申请
- 专利标题： CELL LINES EXPRESSING GABA RECEPTOR AND METHODS USING THEM
- 专利标题（中）： 细胞系表达GABA受体及其使用方法
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申请号： US12865497申请日： 2009-02-02
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公开(公告)号： US20110003711A1公开(公告)日： 2011-01-06
- 发明人: Kambiz Shekdar , Jessica Langer
- 申请人： Kambiz Shekdar , Jessica Langer
- 申请人地址： US NJ New Brunswick
- 专利权人： CHROMOCELL CORPORATION
- 当前专利权人： CHROMOCELL CORPORATION
- 当前专利权人地址： US NJ New Brunswick
- 国际申请： PCT/US2009/032903 WO 20090202
- 主分类号： C40B40/02
- IPC分类号： C40B40/02 ; C12N5/10 ; C12N15/63 ; C12Q1/02 ; G01N33/566 ; C07K16/28 ; C07K2/00
摘要：
The invention relates to Gamma-aminobutyric acid receptors (GABA receptors) as well as cells and cell lines stably expressing a GABA receptor. The invention includes cell lines that express various subunit combinations of GABA receptors. The GABA receptor- and GABA receptor subunit-expressing cell lines are highly sensitive, physiologically relevant and produce consistent results. The invention further provides methods of making such cells and cell lines. The GABA receptor- and GABA receptor subunit-expressing cells and cell lines provided herein are useful in identifying modulators of GABA receptors.
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