发明申请
- 专利标题： COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS
- 专利标题（中）： 化合物和组合物作为激酶抑制剂
-
申请号： US12865339申请日： 2009-01-27
-
公开(公告)号： US20110003798A1公开(公告)日： 2011-01-06
- 发明人: Barun Okram , Tetsuo Uno , Qiang Ding , Yahua Liu , Yunho Jin , Qihui Jin , Xu Wu , Jianwei Che , S. Frank Yan , Xueshi Hao
- 申请人： Barun Okram , Tetsuo Uno , Qiang Ding , Yahua Liu , Yunho Jin , Qihui Jin , Xu Wu , Jianwei Che , S. Frank Yan , Xueshi Hao
- 申请人地址： BM Hamilton
- 专利权人： IRM LLC
- 当前专利权人： IRM LLC
- 当前专利权人地址： BM Hamilton
- 国际申请： PCT/US09/32148 WO 20090127
- 主分类号： A61K31/5415
- IPC分类号： A61K31/5415 ; C07D471/04 ; C07D498/04 ; A61K31/4375 ; A61K31/5377 ; A61K31/506 ; A61K31/496 ; A61K31/541 ; A61K31/497 ; A61K31/538 ; A61K31/5383 ; A61K31/501 ; A61P11/06 ; A61P11/08 ; A61P11/00 ; A61P17/00 ; A61P17/06 ; A61P11/02 ; A61P29/00 ; A61P25/00 ; A61P35/00 ; A61P31/18 ; A61P37/02
摘要：
The invention provides a novel class of 2,7-naphthyridin derivatives; pharmaceutical compositions comprising such compounds and methods of using such compounds to treat o prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Syk, ZAP70, KDR, FMS, FLT*, c-Kit, RET, TrkA, TrkB, TrkC-GR-1R, Alk, c-FMS or combinations thereof.
公开/授权文献
- US08546370B2 Compounds and compositions as kinase inhibitors 公开/授权日：2013-10-01