发明申请
- 专利标题: NOVEL ALPHA-GALACTOSIDASES
- 专利标题(中): 新的阿尔法胶质糖
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申请号: US12709070申请日: 2010-02-19
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公开(公告)号: US20110014170A1公开(公告)日: 2011-01-20
- 发明人: Qiyong Peter LIU , Henrik Clausen
- 申请人: Qiyong Peter LIU , Henrik Clausen
- 专利权人: Velico Medical, Inc.
- 当前专利权人: Velico Medical, Inc.
- 主分类号: A61K35/18
- IPC分类号: A61K35/18 ; A61P7/00 ; C12N5/078 ; C12N9/24
摘要:
This invention relates to novel α-galactosidases for the enzymatic removal of the immunodominant monosaccharides on blood products and tissues. Specifically this invention provides a novel family of α3 glycosidases, used for the enzymatic removal of type B antigens from blood group B and AB reactive blood products, and the Galili antigen from non-human animal tissues, thereby converting these to non-immunogenic cells and tissues suitable for transplantation.
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