发明申请
- 专利标题： Detection Of Truncation Mutations By Mass Spectrometry
- 专利标题（中）： 通过质谱检测截断突变
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申请号： US12850499申请日： 2010-08-04
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公开(公告)号： US20110015369A1公开(公告)日： 2011-01-20
- 发明人: ALEX M. GARVIN , SADANAND GITE , VLADISLAV B. BERGO , KENNETH J. ROTHSCHILD
- 申请人： ALEX M. GARVIN , SADANAND GITE , VLADISLAV B. BERGO , KENNETH J. ROTHSCHILD
- 主分类号： C07K14/00
- IPC分类号： C07K14/00 ; C07K7/08
摘要：
This invention relates to the detection and analysis by mass spec of nascent proteins, and in particular truncated proteins, translated within cellular or cell-free translation systems. N-terminal and C-terminal epitopes introduced into these nascent proteins permit rapid and efficient isolation, as well as mass difference.
公开/授权文献
- US08507648B2 Detection of truncation mutations by mass spectrometry 公开/授权日：2013-08-13
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