A method of allocating a radio resource in a frequency division duplex (FDD) frame in which a downlink frame and an uplink frame are divided in a frequency domain in a wireless communication system includes allocating a downlink resource region for a first system in the downlink frame, and allocating an uplink resource region for the first system to the uplink frame such that the uplink resource region does not temporally overlap with the downlink resource region for the first system, wherein a resource region except for the downlink resource region for the first system is allocated to a downlink resource region for a second system in the downlink frame, and a resource region except for the uplink resource region for the first system is allocated to an uplink resource region for the second system in the uplink frame. When a half-duplex FDD (H-FDD)-type user equipment is supported in a frequency division duplex (FDD) frame supporting heterogeneous systems, radio resources can be effectively utilized by minimizing waste of unnecessary radio resources.