发明申请
- 专利标题： Platinum (IV) Complexes
- 专利标题（中）： 铂（IV）配合物
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申请号： US12665708申请日： 2008-06-18
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公开(公告)号： US20110021483A1公开(公告)日： 2011-01-27
- 发明人: Jan Gysbert Hermanus Du Preez
- 申请人： Jan Gysbert Hermanus Du Preez
- 申请人地址： ZA Pert Elizabeth
- 专利权人： PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED
- 当前专利权人： PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED
- 当前专利权人地址： ZA Pert Elizabeth
- 国际申请： PCT/IB2008/052395 WO 20080618
- 主分类号： A61K31/555
- IPC分类号： A61K31/555 ; C07F15/00 ; A61K31/282 ; C12N5/07 ; A61P35/00
摘要：
Provided are nitroplatinum(IV) complexes containing a bidentate dicarboxylate ligand (e.g., oxalate) which maybe useful treating various forms of proliferative diseases, such as cancer. In some instances the platinum(IV) complexes are relatively stable and may be suitable for oral administration. Also provided are methods of treatment, as well as kits and unit dosages.
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