Projectiles containing a fluorophore composition comprising a fluorophore compound and an activator composition comprising an activator compound for marking targets are disclosed. Some embodiments include a nose structure with a cavity radially segmented into a plurality of radially isolated compartments by at least one laterally and radially extending internal wall. Additional embodiments include a fore compartment and an aft compartment sealed by a septum. Yet additional embodiments include at least one pressurized cavity and may further include a plunger positioned and configured to pierce each pressurized cavity. Methods of manufacturing target marking projectiles and methods of marking targets are also disclosed.