发明申请
- 专利标题: METHOD OF DETECTING BLADDER CANCER
- 专利标题(中): 检测乳腺癌的方法
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申请号: US12988621申请日: 2009-04-21
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公开(公告)号: US20110033386A1公开(公告)日: 2011-02-10
- 发明人: Keiji Inoue , Masahiro Ishizuka
- 申请人: Keiji Inoue , Masahiro Ishizuka
- 专利权人: SBI ALAPROMO CO., LTD.,KOCHI UNVERSITY
- 当前专利权人: SBI ALAPROMO CO., LTD.,KOCHI UNVERSITY
- 优先权: JP2008-111745 20080422
- 国际申请: PCT/JP2009/001821 WO 20090421
- 主分类号: A61K49/00
- IPC分类号: A61K49/00 ; A61K31/197 ; A61P35/00
摘要:
Provided is a sensitizing detection agent of an oral or intravenous administration type which enables the detection of bladder cancer with a higher sensitivity without causing pain to the patient. A sensitizing detection agent for bladder cancer comprising 5-aminolevulinic acid (ALA), a derivative thereof, or a salt of these is orally or intravenously administered, and a video camera system is inserted via the urethra and a blue light at 380-440 nm is irradiated to observe the red fluorescent part. Further, VLD-M1 is inserted and a blue light at 405 nm is irradiated to observe fluorescence intensity (relative intensity) of the red light part. For oral administration, 20 mg/kg (maximum of 1 g) of ALA is dissolved in 50 mL of a 5% glucose solution prior to the administration.
公开/授权文献
- US08999296B2 Method of detecting bladder cancer 公开/授权日:2015-04-07
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