发明申请
US20110033454A1 Methods For Treating Diseases Using Antibodies to Aminophospolipids
审中-公开
用氨基磷脂抗体治疗疾病的方法
- 专利标题： Methods For Treating Diseases Using Antibodies to Aminophospolipids
- 专利标题（中）： 用氨基磷脂抗体治疗疾病的方法
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申请号： US12869283申请日： 2010-08-26
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公开(公告)号： US20110033454A1公开(公告)日： 2011-02-10
- 发明人: PHILIP E. THORPE , SOPHIA RAN
- 申请人： PHILIP E. THORPE , SOPHIA RAN
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K39/00 ; A61P31/12 ; A61P7/06 ; C12Q1/70 ; G01N33/53
摘要：
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
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