发明申请
- 专利标题: Human G-Protein Coupled Receptor
- 专利标题(中): 人类G蛋白偶联受体
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申请号: US12831336申请日: 2010-07-07
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公开(公告)号: US20110033470A1公开(公告)日: 2011-02-10
- 发明人: Yi Li , Craig A. Rosen
- 申请人: Yi Li , Craig A. Rosen
- 申请人地址: US MD Rockville
- 专利权人: Human Genome Sciences, Inc.
- 当前专利权人: Human Genome Sciences, Inc.
- 当前专利权人地址: US MD Rockville
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07H21/04 ; C12N15/63 ; C12N5/10 ; C12P21/02 ; C07K14/705 ; C07K16/28 ; G01N33/566 ; C12Q1/68 ; A61K38/02 ; C07K2/00 ; A61P43/00
摘要:
A human G-protein coupled receptor polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for identifying antagonists and agonists to such polypeptide. Antagonists and agonists may be used therapeutically to inhibit or stimulate the G-protein coupled receptor. Also disclosed are assays for detecting mutations in the nucleic acid sequence encoding the G-protein coupled receptor.
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