发明申请
- 专利标题： SPIROINDOLINES AS MODULATORS OF CHEMOKINE RECEPTORS
- 专利标题（中）： 作为化合物受体的调节剂的螺旋体衍生物
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申请号： US12665335申请日： 2008-06-20
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公开(公告)号： US20110034499A1公开(公告)日： 2011-02-10
- 发明人: Brian W. Budzik , Hilary Schenck Eidam , Ryan Michael Fox , Krista B. Goodman , Dimitar B. Gotchev , Pamela A. Haile , Terry Vincent Hughes , Ronggang Liu , Nathan A. Miller , Tamara Ann Miskowski , Clark A. Sehon , Andrew Q. Viet , Gren Z. Wang , Jing Zhang
- 申请人： Brian W. Budzik , Hilary Schenck Eidam , Ryan Michael Fox , Krista B. Goodman , Dimitar B. Gotchev , Pamela A. Haile , Terry Vincent Hughes , Ronggang Liu , Nathan A. Miller , Tamara Ann Miskowski , Clark A. Sehon , Andrew Q. Viet , Gren Z. Wang , Jing Zhang
- 国际申请： PCT/US08/67589 WO 20080620
- 主分类号： A61K31/438
- IPC分类号： A61K31/438 ; C07D471/10 ; A61P9/10 ; A61P29/00 ; A61P31/16 ; A61P3/00 ; A61P3/10 ; A61P25/00 ; A61P11/06 ; A61P13/12 ; A61P9/04 ; A61P25/28 ; A61P1/00 ; A61P15/00
摘要：
The present invention relates to a compound of the following formula: where R1-R6, R10, Y, n, m, p, and q are as defined herein. Compounds and compositions of the present invention are useful for the treatment of diseases associated with the overexpression of CCR2.
公开/授权文献
- US08431590B2 Spiroindolines as modulators of chemokine receptors 公开/授权日：2013-04-30