Invention Application
- Patent Title: Thiol-Selective Water-Soluble Polymer Derivatives
- Patent Title (中): 硫醇选择性水溶性聚合物衍生物
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Application No.: US12909755Application Date: 2010-10-21
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Publication No.: US20110034643A1Publication Date: 2011-02-10
- Inventor: Antoni Kozlowski , Remy F. Gross, III , Samuel P. McManus
- Applicant: Antoni Kozlowski , Remy F. Gross, III , Samuel P. McManus
- Applicant Address: US CA San Carlos
- Assignee: Nektar Therapeutics
- Current Assignee: Nektar Therapeutics
- Current Assignee Address: US CA San Carlos
- Main IPC: C08G75/00
- IPC: C08G75/00
Abstract:
The present invention provides water-soluble, polymer derivatives having a thiol-selective terminus suitable for selective coupling to thiol groups, such as those contained in the cysteine residues of proteins, as well as methods for preparing the water-soluble, polymer derivatives having a thiol-selective terminus.
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