发明申请
- 专利标题： Fused Phenyl Amido Heterocyclic Compounds
- 专利标题（中）： 熔融苯基酰胺杂环化合物
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申请号： US12913059申请日： 2010-10-27
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公开(公告)号： US20110039821A1公开(公告)日： 2011-02-17
- 发明人: Hao Bai , Simon Bailey , Dilip Ramakant Bhumralkar , Feng C. Bi , Fengli Guo , Mingying He , Paul Stuart Humphries , Anthony Lai Ling , Jihong Lou , Seiji Nukui , Ru Zhou
- 申请人： Hao Bai , Simon Bailey , Dilip Ramakant Bhumralkar , Feng C. Bi , Fengli Guo , Mingying He , Paul Stuart Humphries , Anthony Lai Ling , Jihong Lou , Seiji Nukui , Ru Zhou
- 专利权人： Pfizer Inc
- 当前专利权人： Pfizer Inc
- 主分类号： A61K31/397
- IPC分类号： A61K31/397 ; C07D405/12 ; A61K31/443 ; C07D401/14 ; A61K31/4155 ; C07D403/14 ; C07D401/12 ; A61K31/4709 ; A61K31/4439 ; C07D413/12 ; A61K31/423 ; C07D403/12 ; A61K31/497 ; A61K31/4192 ; A61P3/00
摘要：
The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).
公开/授权文献
- US08119624B2 Fused phenyl amido heterocyclic compounds 公开/授权日：2012-02-21