Invention Application
US20110039869A1 COMPOSITION FOR INHIBITING THE ACTIVITY OF INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR SUBTYPE III
审中-公开
用于抑制INOSITOL 1,4,5-三磷酸酯受体亚型III活性的组合物
- Patent Title: COMPOSITION FOR INHIBITING THE ACTIVITY OF INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR SUBTYPE III
- Patent Title (中): 用于抑制INOSITOL 1,4,5-三磷酸酯受体亚型III活性的组合物
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Application No.: US12865128Application Date: 2008-01-31
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Publication No.: US20110039869A1Publication Date: 2011-02-17
- Inventor: Justin Changjoon Lee , Sang-Soo Kang , Kyung-Suk Han , Eun-Joo Roh , Jae-Yong Park
- Applicant: Justin Changjoon Lee , Sang-Soo Kang , Kyung-Suk Han , Eun-Joo Roh , Jae-Yong Park
- Applicant Address: KR Seoul
- Assignee: Korea Institute of Science and Technology
- Current Assignee: Korea Institute of Science and Technology
- Current Assignee Address: KR Seoul
- Priority: KR10-2008-0010156 20080131
- International Application: PCT/KR08/00603 WO 20080131
- Main IPC: A61K31/522
- IPC: A61K31/522 ; A61P29/00 ; A61P25/00 ; A61P25/30 ; A61P35/00 ; A61P3/10 ; A61P13/10 ; A61P9/00 ; A61P9/12 ; A61P9/10 ; A61P13/12
Abstract:
An agent for inhibiting the activity of inositol-1,4,5-triphospate receptor subtype 3 (IP3R3), containing caffeine and/or its analogs, and/or their pharmaceutically acceptable salts, as an active ingredient, is provided. A composition for preventing and/or treating a disease associated with Ca2+ release through IP3R3, containing the IP3R3 inhibiting agent, is also provided.
Information query
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