The described aspects relate to systems and methods for power control in wireless communication systems. In particular, the described aspects relate to dynamically providing, based on activities on HSUPA channels, a downlink power control adjustment during a data transmission from a user equipment device to a base station or node B device in a HSUPA communication system. The method determines a Signal-to-Interference Ratio (SIR) target for the Enhanced Transport Channel (E-DCH) based on a transmitter's logic that determines the required power level of the downlink grant control channels. This target can then apply to the final target determined on a plurality of other transport channels for the receiver to adjust the power of its downlink channels.