发明申请
US20110044968A1 COMPOSITIONS FOR TREATMENT WITH METALLOPEPTIDASES, METHODS OF MAKING AND USING THE SAME
审中-公开
用于治疗金属蛋白酶的组合物,制备和使用它们的方法
- 专利标题: COMPOSITIONS FOR TREATMENT WITH METALLOPEPTIDASES, METHODS OF MAKING AND USING THE SAME
- 专利标题(中): 用于治疗金属蛋白酶的组合物,制备和使用它们的方法
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申请号: US12921670申请日: 2009-03-10
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公开(公告)号: US20110044968A1公开(公告)日: 2011-02-24
- 发明人: Elijah M. Bolotin , Gerardo Castillo , Penelope Markham , Manshun Lai
- 申请人: Elijah M. Bolotin , Gerardo Castillo , Penelope Markham , Manshun Lai
- 申请人地址: US WA Seattle
- 专利权人: Pharmal N Corporation
- 当前专利权人: Pharmal N Corporation
- 当前专利权人地址: US WA Seattle
- 国际申请: PCT/US09/36648 WO 20090310
- 主分类号: A61K38/54
- IPC分类号: A61K38/54 ; C12N9/96 ; A61P31/00 ; A61P25/28
摘要:
The present invention is directed to biocompatible compositions and the use of metal bridges to connect a back-bone and a metallopeptidase active agent. In certain instances, the subject compositions provide a means of achieving sustained release of the metallopeptidase active agent after administration to a subject.