发明申请
US20110053260A1 RECOMBINANT POXVIRUS EXPRESSING HOMOLOGOUS GENES INSERTED INTO THE POXVIRAL GENOME
审中-公开
重组蛋白表达插入到基因组中的同源基因
- 专利标题: RECOMBINANT POXVIRUS EXPRESSING HOMOLOGOUS GENES INSERTED INTO THE POXVIRAL GENOME
- 专利标题(中): 重组蛋白表达插入到基因组中的同源基因
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申请号: US12894589申请日: 2010-09-30
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公开(公告)号: US20110053260A1公开(公告)日: 2011-03-03
- 发明人: PAUL HOWLEY , Sonja Leyrer
- 申请人: PAUL HOWLEY , Sonja Leyrer
- 优先权: DKPA200200752 20020516; DKPA200200753 20020516
- 主分类号: C12N15/63
- IPC分类号: C12N15/63
摘要:
The present invention relates to a recombinant poxvirus vector capable of expressing two or more homologous, foreign sequences, which derive from different variants of a microorganism, and which have a homology of 50% or above. The invention further relates to a method for preparing such recombinant poxvirus and the use of such recombinant poxvirus as medicament or vaccine. Additionally, a method for affecting preferably inducing, an immune response in a living animal, including a human, is provided.
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