Example methods and apparatus to adjust control loop timing in a process control system are disclosed. A disclosed example method includes receiving a first input signal generated via a first process control device within a process control system, determining within the process control system if the first input signal is received during a first scheduled time period of a control loop, and adjusting within the process control system a timing of a subsequent input signal received from the first process control device to cause the subsequent input signal to be received during a subsequent scheduled time period of the control loop, wherein the timing of the subsequent input signal is based on at least when the first input signal was received.