发明申请
US20110059019A1 NOVEL ARYL PIPERAZINE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE AND SEROTONIN RECEPTORS
审中-公开
新型ARYL PIPERAZINE衍生物作为DOPAMINE和SEROTONIN受体的调节剂有用
- 专利标题: NOVEL ARYL PIPERAZINE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE AND SEROTONIN RECEPTORS
- 专利标题(中): 新型ARYL PIPERAZINE衍生物作为DOPAMINE和SEROTONIN受体的调节剂有用
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申请号: US12865410申请日: 2009-01-29
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公开(公告)号: US20110059019A1公开(公告)日: 2011-03-10
- 发明人: Dan Peters , Lars Christian Rønn , Karin Sandager Nielsen , Jørgen Scheel-Krüger
- 申请人: Dan Peters , Lars Christian Rønn , Karin Sandager Nielsen , Jørgen Scheel-Krüger
- 申请人地址: DK Ballerup
- 专利权人: NeuroSearch A/S
- 当前专利权人: NeuroSearch A/S
- 当前专利权人地址: DK Ballerup
- 优先权: DKPA200800149 20080201
- 国际申请: PCT/EP09/50999 WO 20090129
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D401/14 ; A61K49/00 ; A61P25/00 ; A61P25/14 ; A61P29/00 ; A61P15/00 ; A61P25/30 ; A61P25/22 ; A61P25/18
摘要:
This invention provides novel aryl piperazine derivatives having medical utility, in particular as modulators of dopamine and serotonin receptors, preferably the D3, 5HT1A and 5-HT2A receptor subtypes, and in particular useful for the treatment of neuropsychiatric disorders, incl. schizophrenia.