发明申请
- 专利标题: LONIDAMINE ANALOGUES FOR FERTILITY MANAGEMENT
- 专利标题(中): 用于肥胖管理的LONIDAMINE ANALOGUES
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申请号: US12830681申请日: 2010-07-06
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公开(公告)号: US20110060003A1公开(公告)日: 2011-03-10
- 发明人: Ingrid Gunda Georg , Joseph S. Tash , Ramappa Chakrasali , Sudhakar Rao Jakkaraj , Katherine Roby
- 申请人: Ingrid Gunda Georg , Joseph S. Tash , Ramappa Chakrasali , Sudhakar Rao Jakkaraj , Katherine Roby
- 主分类号: A61K31/416
- IPC分类号: A61K31/416 ; A61K31/437 ; A61P3/00 ; A61P15/00
摘要:
Fertility management can include: administering to the subject one or more doses of a compound according to Formula I so as to reduce fertility in the subject. Fertility management can also include administering an effective amount of the compound to: impair Sertoli cell function in a male subject; inhibit spermatogenesis in the subject; reduce testis weight in the subject; reduce ovary weight in a female subject; reduce serum progesterone in the female subject; impair ovarian follicle function in the female subject; causing reversible fertility in the subject. In order to return fertility, the method can include ceasing administration of the compound to the subject so as to return fertility in the subject. The compound can be administered for irreversibly sterilizing the subject.
公开/授权文献
- US08377958B2 Lonidamine analogues for fertility management 公开/授权日:2013-02-19
信息查询
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