Embodiments of a four-port isolation module are presented herein. In an embodiment, the isolation module includes a step-up autotransformer comprising a first and second winding that are electrically coupled in series at a center node. The first port of the isolation module is configured to couple an antenna to a first end node of the series coupled windings. The second port of the isolation module is configured to couple a balancing network to a second end node of the series coupled windings. The third port is configured to couple a transmit path to the center node. The fourth port is configured to couple a differential receive path across the first end node and the second end node. The isolation module effectively isolates the third port from the fourth port to prevent strong outbound signals received at the third port from saturating an LNA coupled to the fourth port.