Invention Application
- Patent Title: IRE-1alpha INHIBITORS
- Patent Title (中): IRE-1α抑制剂
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Application No.: US12941530Application Date: 2010-11-08
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Publication No.: US20110065162A1Publication Date: 2011-03-17
- Inventor: JOHN B. PATTERSON , DAVID G. LONERGAN , GARY A. FLYNN , QINGPING ZENG , PETER V. PALLAI
- Applicant: JOHN B. PATTERSON , DAVID G. LONERGAN , GARY A. FLYNN , QINGPING ZENG , PETER V. PALLAI
- Applicant Address: US CA VALENCIA
- Assignee: MANNKIND CORPORATION
- Current Assignee: MANNKIND CORPORATION
- Current Assignee Address: US CA VALENCIA
- Main IPC: C12N9/99
- IPC: C12N9/99
Abstract:
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
Public/Granted literature
- US08614253B2 IRE-1α inhibitors Public/Granted day:2013-12-24
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