发明申请
- 专利标题: PYRROLOPYRIDINES AS KINASE INHIBITORS
- 专利标题(中): 吡咯啉作为激酶抑制剂
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申请号: US12992468申请日: 2009-05-13
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公开(公告)号: US20110070317A1公开(公告)日: 2011-03-24
- 发明人: Yvan Le Huerou , James F. Blake , Indrani W. Gunawardana , Peter J. Mohr , Eli M. Wallace , Bin Wang , Mark Joseph Chicarelli , Michael Lyon
- 申请人: Yvan Le Huerou , James F. Blake , Indrani W. Gunawardana , Peter J. Mohr , Eli M. Wallace , Bin Wang , Mark Joseph Chicarelli , Michael Lyon
- 申请人地址: US CO Boulder
- 专利权人: ARRAY BIOPHARMA INC.
- 当前专利权人: ARRAY BIOPHARMA INC.
- 当前专利权人地址: US CO Boulder
- 国际申请: PCT/US2009/043691 WO 20090513
- 主分类号: A61K33/24
- IPC分类号: A61K33/24 ; A61P35/00 ; C07D471/04 ; A61K31/437 ; A61K31/7068 ; A61K31/4745 ; A61K31/513 ; A61K31/497 ; A61K31/506 ; A61K31/501 ; A61K31/498 ; A61K31/5377 ; A61K31/55
摘要:
Compounds of Formula (I) are useful for inhibition of CHK1 and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
公开/授权文献
- US08178131B2 Pyrrolopyridines as kinase inhibitors 公开/授权日:2012-05-15