发明申请
- 专利标题： IMMUNOSTIMULATORY NUCLEIC ACID MOLECULES
- 专利标题（中）： 免疫细胞核酸分子
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申请号： US12946227申请日： 2010-11-15
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公开(公告)号： US20110081366A1公开(公告)日： 2011-04-07
- 发明人: Arthur M. Krieg
- 申请人： Arthur M. Krieg
- 申请人地址： US IA Iowa City
- 专利权人： University of Iowa Research Foundation
- 当前专利权人： University of Iowa Research Foundation
- 当前专利权人地址： US IA Iowa City
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61P31/00 ; A61P35/00
摘要：
Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful as a synthetic adjuvant.
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