发明申请
- 专利标题： Low Temperature, Single Solvent Process for the Production of Sucrose-6-Ester
- 专利标题（中）： 用于生产蔗糖-6-酯的低温单溶剂方法
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申请号： US12901808申请日： 2010-10-11
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公开(公告)号： US20110087018A1公开(公告)日： 2011-04-14
- 发明人: Edward Micinski , David Coleman , James Edwin Wiley, JR.
- 申请人： Edward Micinski , David Coleman , James Edwin Wiley, JR.
- 申请人地址： GB London
- 专利权人： Tate & Lyle Technology Limited
- 当前专利权人： Tate & Lyle Technology Limited
- 当前专利权人地址： GB London
- 主分类号： C07H1/00
- IPC分类号： C07H1/00
摘要：
A method for the preparation of a sucrose-6-ester is disclosed. In a first step of the method, sucrose in a polar aprotic solvent is reacted with an organotin-based acylation promoter. The water of reaction is removed at a temperature that does not exceed about 80° C. In one aspect, the water is removed by distillation of part of the polar aprotic solvent at reduced pressure. In a second step, a carboxylic acid anhydride is added. In one aspect, the resulting reaction mixture is maintained at a temperature of 10° C. or less for a period of time sufficient to produce a sucrose-6-ester. The sucrose-6-ester can be converted to sucralose.