发明申请
US20110098270A1 THIAZOLOPYRIMIDINES AND THEIR USE AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3 KINASE
有权
噻唑啉酮和它们作为磷脂酰肌醇-3激酶的抑制剂
- 专利标题： THIAZOLOPYRIMIDINES AND THEIR USE AS INHIBITORS OF PHOSPHATIDYLINOSITOL-3 KINASE
- 专利标题（中）： 噻唑啉酮和它们作为磷脂酰肌醇-3激酶的抑制剂
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申请号： US12986317申请日： 2011-01-07
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公开(公告)号： US20110098270A1公开(公告)日： 2011-04-28
- 发明人: Timothy Colin Hancox , Neil Anthony Pegg , Mandy Christine Beswick , Toby Jonathan Blench , Elsa Amandine Dechaux , Jahusz Jozef Kulagowski , Alan John Nadin , Stephen Price
- 申请人： Timothy Colin Hancox , Neil Anthony Pegg , Mandy Christine Beswick , Toby Jonathan Blench , Elsa Amandine Dechaux , Jahusz Jozef Kulagowski , Alan John Nadin , Stephen Price
- 优先权： GB0711344.2 20070612; GB0715677.1 20070810
- 主分类号： A61K31/397
- IPC分类号： A61K31/397 ; A61K31/5377 ; A61P35/00
摘要：
Thiazolopyrimidine compounds of formula I, where W represents a thiazole ring, selectively inhibit the p110 delta subtype of PI3 Kinase (PI3K), and are useful for treating diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
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