发明申请
US20110105528A1 1-(7-(HEXAHYDROPYRROLO [3, 4-C] PYRROL-2 (1H)-YL) QUINOLIN-4-YL) -3- (PYRAZIN-2-YL) UREA DERIVATIVES AND RELATED COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK-3)
有权
1-（7-（六氢吡喃并[3,4-C]吡咯-2（1H） - 基）喹啉-4-基）-3-（吡嗪-2-基）脲衍生物和相关化合物作为GLYCOGEN SYNTHASE KINASE 3（ GSK-3）
![1-(7-(HEXAHYDROPYRROLO [3, 4-C] PYRROL-2 (1H)-YL) QUINOLIN-4-YL) -3- (PYRAZIN-2-YL) UREA DERIVATIVES AND RELATED COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK-3)](/docs/US/2011-05-05/US20110105528A1/abs.jpg.600x600.jpg)
- 专利标题： 1-(7-(HEXAHYDROPYRROLO [3, 4-C] PYRROL-2 (1H)-YL) QUINOLIN-4-YL) -3- (PYRAZIN-2-YL) UREA DERIVATIVES AND RELATED COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK-3)
- 专利标题（中）： 1-（7-（六氢吡喃并[3,4-C]吡咯-2（1H） - 基）喹啉-4-基）-3-（吡嗪-2-基）脲衍生物和相关化合物作为GLYCOGEN SYNTHASE KINASE 3（ GSK-3）
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申请号： US12988833申请日： 2009-04-24
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公开(公告)号： US20110105528A1公开(公告)日： 2011-05-05
- 发明人: Sean Colm Turner , Margaretha Henrica Maria Bakker , Wilfried Hornberger
- 申请人： Sean Colm Turner , Margaretha Henrica Maria Bakker , Wilfried Hornberger
- 申请人地址： DE Wiesbaden
- 专利权人： Abbott GmbH & Co. KG
- 当前专利权人： Abbott GmbH & Co. KG
- 当前专利权人地址： DE Wiesbaden
- 优先权： EP08155133.5 20080424
- 国际申请： PCT/EP2009/054987 WO 20090424
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; C07D403/14 ; C07D405/14 ; A61K31/4709 ; A61P25/18 ; A61P25/28 ; A61P25/16 ; A61P19/02
![1-(7-(HEXAHYDROPYRROLO [3, 4-C] PYRROL-2 (1H)-YL) QUINOLIN-4-YL) -3- (PYRAZIN-2-YL) UREA DERIVATIVES AND RELATED COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK-3)](/abs-image/US/2011/05/05/US20110105528A1/abs.jpg.150x150.jpg)
摘要：
The present invention relates to novel heterocyclic compounds which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
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