A control handle for use with a steerable endoscopic device. The endoscopic device having a pair of control wires to effect steering. The control handle includes a steering mechanism that includes an actuator, such as a control knob, drivingly connected to a drive member, such as a sprocket or drive gear. To transmit force from the drive member to the control wires, a length of transmission structure, such as bead chain, is connected to the proximal ends of the control wires and is engaged with the drive member. In one embodiment, a single-use endoscope may be provided, which includes a control handle, a steerable endoscopic device, and a umbilical cord or communications conduit for functionally connecting the control handle to a control cabinet of an endoscopic imaging system.