发明申请
- 专利标题: VIRUS VECTOR AND USE THEREOF
- 专利标题(中): 病毒矢量及其使用
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申请号: US12450999申请日: 2008-04-11
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公开(公告)号: US20110107466A1公开(公告)日: 2011-05-05
- 发明人: Masashi Mori , Koji Dohi
- 申请人: Masashi Mori , Koji Dohi
- 优先权: JP2007-120181 20070427
- 国际申请: PCT/JP2008/057170 WO 20080411
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C12N15/63 ; A01H5/00 ; C12N5/10 ; C12P21/00
摘要:
It is intended to provide a polynucleotide comprising a viral base sequence, the viral base sequence containing: a first base sequence encoding a viral replication protein, and a second base sequence encoding a viral movement protein, the second base sequence being located downstream of the first base sequence and having a linking site for linking with an exogenous base sequence encoding a polypeptide to be expressed, the linking site being located downstream of the second base sequence, the second base sequence being obtained by modifying with a base sequence in a native sequence derived from a virus by insertion, substitution, or addition. By using this, a vector containing a viral base sequence is constructed, and a protein is efficiently produced without worsening growth of a host cell containing the vector.
公开/授权文献
- US08586826B2 Virus vector and use thereof 公开/授权日:2013-11-19
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