发明申请
- 专利标题： METHOD FOR PROFILING DRUG COMPOUNDS
- 专利标题（中）： 化合物化合物的分析方法
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申请号： US12736468申请日： 2009-04-10
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公开(公告)号： US20110111980A1公开(公告)日： 2011-05-12
- 发明人: René Houtman , Robby Ruijtenbeek
- 申请人： René Houtman , Robby Ruijtenbeek
- 优先权： EP08154419.9 20080411
- 国际申请： PCT/EP2009/054358 WO 20090410
- 主分类号： C40B30/06
- IPC分类号： C40B30/06 ; C40B40/10
摘要：
The present invention relates to systems and methods for testing kinase inhibition using an array of substrates, in particular protein kinase substrates, preferably immobilized on a porous matrix. More particularly, the method provides kinase inhibition profiles of kinase inhibitors using phosphorylation patterns. The present invention can therefore be used to predict the response of cells, tissues, organs and/or warm-blooded animals to a drug, to determine the clinical outcome of a drug therapy and for diagnostical and prognostical purposes.
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