Invention Application
US20110112020A1 MEASUREMENT OF G-PROTEIN mRNA IN THE DIAGNOSIS OF GROWTH HORMONE INSUFFICIENCY
审中-公开
G蛋白mRNA在生长激素缺失诊断中的测定
- Patent Title: MEASUREMENT OF G-PROTEIN mRNA IN THE DIAGNOSIS OF GROWTH HORMONE INSUFFICIENCY
- Patent Title (中): G蛋白mRNA在生长激素缺失诊断中的测定
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Application No.: US12771377Application Date: 2010-04-30
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Publication No.: US20110112020A1Publication Date: 2011-05-12
- Inventor: Jill D. Jacobson , Mark Clements
- Applicant: Jill D. Jacobson , Mark Clements
- Applicant Address: US MO Kansas City
- Assignee: THE CHILDREN'S MERCY HOSPITAL
- Current Assignee: THE CHILDREN'S MERCY HOSPITAL
- Current Assignee Address: US MO Kansas City
- Main IPC: A61K38/25
- IPC: A61K38/25 ; C12Q1/68 ; A61P5/06
Abstract:
The present invention is directed towards a diagnostic test, treatment, and monitoring of treatment for growth hormone abnormalities including Growth Hormone Deficiency (“GHD”) as well as a kit comprising the necessary components of the present invention. G-protein expression and levels of mRNA are evaluated to determine if a patient has GHD or if treatment for GHD is effective. A G-protein agonist or antagonist is used to treat GHD by bringing G-protein expression and levels of mRNA into the normal range.
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