- 专利标题: ORALLY ACTIVE CURCUMINOID COMPOUNDS
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申请号: US13002588申请日: 2009-07-06
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公开(公告)号: US20110112190A1公开(公告)日: 2011-05-12
- 发明人: Ramchand Nanappan Chaniyilparampu , Anitha Krishnan Nair , Anuj Kapoor , Kiran Bhupathiraju , Rama Raju Gokaraju , Ganga Raju Gokaraju , Trimurtulu Golakoti , Venkateswarlu Somepalli
- 申请人: Ramchand Nanappan Chaniyilparampu , Anitha Krishnan Nair , Anuj Kapoor , Kiran Bhupathiraju , Rama Raju Gokaraju , Ganga Raju Gokaraju , Trimurtulu Golakoti , Venkateswarlu Somepalli
- 申请人地址: IN CHENNAI
- 专利权人: LAILA PHARMACEUTICALS PVT. LTD.
- 当前专利权人: LAILA PHARMACEUTICALS PVT. LTD.
- 当前专利权人地址: IN CHENNAI
- 优先权: IN1641/CHE/2008 20080707
- 国际申请: PCT/IN09/00382 WO 20090706
- 主分类号: A61K31/232
- IPC分类号: A61K31/232 ; C07C69/587 ; C07C69/602 ; C07C67/08 ; A61P39/06 ; A61P25/28
摘要:
The invention discloses a compound of formula (I) wherein, at least one of R1, R2, R3 and R4 is —C(═O)Rn and R1, R2R3 and R4 are H or CH3 and Rn is alkyl or alkenyl group. The alkenyl group have one or more number of double bonds either in cis form or trans form or both. In Rn, where n is 12 to 30 carbons; and pharmaceutically acceptable salt thereof. The said alkenyl groups are preferably selected from the group consisting of eicosapentaenoic acid (EPA) or DHA (docosahexaenoic acid). This invention further discloses processes for their preparation of compounds of formula I and pharmaceutical compositions that contain these compounds.
公开/授权文献
- US08680143B2 Orally active curcuminoid compounds 公开/授权日:2014-03-25