发明申请
- 专利标题: MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF
- 专利标题(中): 5-HT受体的调节剂及其使用方法
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申请号: US12950029申请日: 2010-11-19
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公开(公告)号: US20110118231A1公开(公告)日: 2011-05-19
- 发明人: Irini Akritopoulou-Zanze , Wilfried Braje , Stevan W. Djuric , Noel S. Wilson , Sean C. Turner , Albert W. Kruger , Ana-Lucia Relo , Shashank Shekhar , Dennie S. Welch , Hongyu Zhao , Jorge Gandarilla , Alan F. Gasiecki , Huanqiu Li , Christina M. Thompson , Min Zhang
- 申请人: Irini Akritopoulou-Zanze , Wilfried Braje , Stevan W. Djuric , Noel S. Wilson , Sean C. Turner , Albert W. Kruger , Ana-Lucia Relo , Shashank Shekhar , Dennie S. Welch , Hongyu Zhao , Jorge Gandarilla , Alan F. Gasiecki , Huanqiu Li , Christina M. Thompson , Min Zhang
- 申请人地址: US IL Abbott Park DE Ludwigshafen
- 专利权人: ABBOTT LABORATORIES,ABBOTT GMBH & CO. KG
- 当前专利权人: ABBOTT LABORATORIES,ABBOTT GMBH & CO. KG
- 当前专利权人地址: US IL Abbott Park DE Ludwigshafen
- 主分类号: A61K31/554
- IPC分类号: A61K31/554 ; C07D487/04 ; C07D491/044 ; C07D513/04 ; A61K31/55 ; A61K31/407 ; A61P25/28 ; A61P25/00 ; A61P25/18 ; A61P25/24 ; A61P25/22 ; A61P25/16 ; A61P25/08 ; A61P25/06 ; A61P25/30 ; A61P3/04 ; A61P3/10 ; A61P9/12 ; A61P29/00 ; A61P15/10 ; A61P15/00 ; A61P17/06
摘要:
The present application relates to aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[c]pyrrole, and octahydrocyclohepta[c]pyrrole derivatives of formula (I) wherein R1, R2, R3, R4, R5, A, Y1, Y2, and Y3 are as defined in the specification. The present application also relates to compositions comprising such compounds, processes for making such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.
公开/授权文献
- US08846951B2 Modulators of 5-HT receptors and methods of use thereof 公开/授权日:2014-09-30
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