发明申请
US20110124702A1 Nanosuspension of a Poorly Soluble Drug via Microfluidization Process
有权
通过微流化过程的难溶性药物的纳米悬浮液
- 专利标题： Nanosuspension of a Poorly Soluble Drug via Microfluidization Process
- 专利标题（中）： 通过微流化过程的难溶性药物的纳米悬浮液
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申请号： US12942930申请日： 2010-11-09
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公开(公告)号： US20110124702A1公开(公告)日： 2011-05-26
- 发明人: Ming J. CHEN , Ho-Wah Hui , Thomas Lee , Paul Kurtulik , Sekhar Surapaneni
- 申请人： Ming J. CHEN , Ho-Wah Hui , Thomas Lee , Paul Kurtulik , Sekhar Surapaneni
- 主分类号： A61K31/4035
- IPC分类号： A61K31/4035 ; A61P9/00 ; A61P31/12 ; A61P35/00 ; A61P29/00 ; A61P11/06 ; A61P19/02 ; B82Y5/00
摘要：
Provided are compositions and methods for preparation and administration of an oral nanosuspension of a poorly soluble drug with improved bioavailability. The method is optimized through microfluidization process with water soluble polymeric excipients in the absence of surfactants.
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