发明申请
- 专利标题： CYCLOSPORIN ANALOG FORMULATIONS
- 专利标题（中）： 环磷酰胺类似物制剂
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申请号： US12941907申请日： 2010-11-08
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公开(公告)号： US20110136744A1公开(公告)日： 2011-06-09
- 发明人: Selvaraj A. Naicker , Randall W. Yatscoff , Robert T. Foster
- 申请人： Selvaraj A. Naicker , Randall W. Yatscoff , Robert T. Foster
- 申请人地址： CA Edmonton
- 专利权人： Isotechnika Inc.
- 当前专利权人： Isotechnika Inc.
- 当前专利权人地址： CA Edmonton
- 主分类号： A61K38/13
- IPC分类号： A61K38/13 ; A61P37/06
摘要：
The present disclosure relates to formulations containing cyclosporin analogs that are structurally similar to cyclosporin A, in particular isomeric mixtures of cyclosporin analogs that are structurally similar to cyclosporin A. The formulations form stable microemulsion preconcentrates and may provide superior drug bioavailability and/or may reduce one or more adverse effects associated with the administration of cyclosporin. Also disclosed are methods for using and preparing the formulations.
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