发明申请
- 专利标题: IgA Nephropathy Testing Method And Test Kit
- 专利标题(中): IgA肾病检测方法及检测试剂盒
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申请号: US12995507申请日: 2009-05-29
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公开(公告)号: US20110143382A1公开(公告)日: 2011-06-16
- 发明人: Takashi Obara , Sadaaki Mizoguchi , Osamu Hotta
- 申请人: Takashi Obara , Sadaaki Mizoguchi , Osamu Hotta
- 申请人地址: JP Tokyo
- 专利权人: Eisai R & D Management Co., Ltd.
- 当前专利权人: Eisai R & D Management Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 优先权: JP2008-144883 20080602
- 国际申请: PCT/JP2009/059873 WO 20090529
- 主分类号: G01N33/53
- IPC分类号: G01N33/53
摘要:
There is provided a renal disease testing method comprising a complex detection step of detecting a complex of an antigen derived from human renal mesangial cells and human IgA in a sample derived from urine collected from a subject. It is preferred that the renal disease testing method of the invention further comprises a determination step of assessing the whether the renal disease is IgA nephropathy based on the ratio of the amount of the complex detected in the complex detection step to the amount of urinary proteins in the sample. The renal disease testing method of the invention has good detection sensitivity and specificity, and can conveniently and safely assess the existence of a renal disease (preferably, IgA nephropathy).
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