发明申请
US20110144073A1 GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY
有权
通过位置21中的芳香链接蛋白连接到硝酸盐的葡萄糖结合蛋白及其在眼科学中的应用
- 专利标题： GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY
- 专利标题（中）： 通过位置21中的芳香链接蛋白连接到硝酸盐的葡萄糖结合蛋白及其在眼科学中的应用
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申请号： US13056921申请日： 2009-07-07
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公开(公告)号： US20110144073A1公开(公告)日： 2011-06-16
- 发明人: Francesca Benedini , Annalisa Bonfanti , Valerio Chiroli , Rebecca Steele , Ennio Ongini , Stefano Biondi
- 申请人： Francesca Benedini , Annalisa Bonfanti , Valerio Chiroli , Rebecca Steele , Ennio Ongini , Stefano Biondi
- 专利权人： NICOX S.A.
- 当前专利权人： NICOX S.A.
- 国际申请： PCT/EP09/58572 WO 20090707
- 主分类号： A61K31/58
- IPC分类号： A61K31/58 ; C07J71/00 ; A61P29/00 ; A61P27/02
摘要：
The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
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