发明申请
US20110152316A1 3,4-SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS
审中-公开
作为RININ抑制剂的3,4-取代的哌啶衍生物
- 专利标题： 3,4-SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS
- 专利标题（中）： 作为RININ抑制剂的3,4-取代的哌啶衍生物
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申请号： US12993127申请日： 2009-05-21
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公开(公告)号： US20110152316A1公开(公告)日： 2011-06-23
- 发明人: Austin Chih-Yu Chen , Daniel Dube , Pierre-Andre Fournier , Erich L. Grimm , Patrick Lacombe , Sebastien Laliberte , Dwight MacDonald , D. Bruce MacKay , Daniel James McKay , Tom Yao-Hsiang Wu
- 申请人： Austin Chih-Yu Chen , Daniel Dube , Pierre-Andre Fournier , Erich L. Grimm , Patrick Lacombe , Sebastien Laliberte , Dwight MacDonald , D. Bruce MacKay , Daniel James McKay , Tom Yao-Hsiang Wu
- 国际申请： PCT/CA2009/000704 WO 20090521
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; C07D401/04 ; A61P9/12 ; A61P9/00 ; A61P11/00 ; A61P13/12 ; A61P27/06 ; A61P15/10 ; A61P25/22
摘要：
The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position Isoqumolone and having the Formula (I): The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.
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